The most widely used cell lines in the bioprocess industry originate from CHO cells. With the large number of CHO clones in use, it is important to have a cell culture medium that supports high viable cell counts and productivity with multiple cell clones. A precise balance of nutrients is crucial for the optimal performance of these cell clones. ActiPro cell culture medium and feed supplements has a tailored formulation that supports viable cell counts of more than 25 million cells per mL and protein production greater than 5 grams per liter. High viable cell density and productivity across multiple CHO cell clones, from shake flasks to 50 L bioreactor cultures, demonstrate the versatility and scalability of the ActiPro medium and Cell Boost supplements.