Scaling In-Line Buffer Preparation from Process Development to Manufacturing
Karolina Busson, Enrique Carredano, Jenny Dunker, and Therese Westman,
,Cytiva
Preparing buffers for large-scale chromatography requires significant resources: time, money, and storage space. Inline conditioning (IC) is one possible way to address these challenges. At the same time, process changes in biomanufacturing require downscaling models. This poster demonstrates how ÄKTA™ avant can be used to replicate the BioProcess™ IC System in bench scale.