Search results for " production"
Article
What’s New in Upstream Technologies
…ession and concentration of viral drug substance suited for R&D activities and clinical material production (1). The system features a modular, scalable, fixed-bed bioreactor for enhanced upstream pr…
Article
Achieving Process Balance with Perfusion Bioreactors
“Suppliers and many others in the industry are looking at how further design and development can optimize the production environment. As the industry pushes towards process intensification and even co…
Article
Speed and Flexibility Are Dual Goals for Biopharma Operations
…cturing increases capacity, contract manufacturers and drug sponsors are investing in facilities and production lines to accommodate clinical trial and commercial needs for innovator and biosimilar d…
Article
Improving Process-Scale Chromatography
Thermo Fisher has introduced a new platform technology with large-scale production capability based on affinity chromatography resins that address challenges in the purification of mAbs, antibody frag…
Article
A Q&A with Eric Langer: CMOs Embrace New Technology
What patterns are you seeing in the use of single-use systems for scale-up and commercial production for CMOs versus drug companies that manufacture their own products?
Commercial-scale bioprocess…
Article
Downstream Processing Continues to Worry CMOs
… to BioPlan Associates 13th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production
(1). In fact, nearly two-thirds (64%) of CMOs surveyed for the study report at leas…
Article
Innovative Therapies Require Modern Manufacturing Systems
At the same time, though, the development of such innovative and targeted therapies heightens the importance of establishing production systems and processes capable of fast scale-up of high-quality c…
Article
Best Practices in Qualification of Single-Use Systems
Single-use bioreactors are widely used in cell line expansion, and the use at production scale is increasing, notably in contract manufacturing. Single-use buffer filtration system and storage bag app…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Jun 15, 2015
By Agnes Shanley
BioPharm International eBooks
Volume 28, Issue 13
Whether outsourcing or developing cell therapies in-house, success demands a focus on quality, c…
Article
Trends in Single-use Bioreactors
Sherman (Sartorius): Currently, there are already good single-use bioreactors for fed-batch and continuous processes up to the 2000 L scale, which today is seen as the production scale of the future g…