Search results for " packing"
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Increasing product titers in upstream cell culture processes pose challenges to downstream purification processes. For efficient operations, downstream purification needs to be able to handle high p…
Article
Advancing Single-Use Technology Through Collaboration
By working together to harmonize the highly variable steps within the biopharmaceutical manufacturing process, both end users and suppliers are making strides toward the efficiency and integrity of …
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Improving Process-Scale Chromatography
… “push button” automation of all chromatography unit operations, including clean-in-place (CIP), packing, run, and unpacking steps. The aim, according to Ljungqvist, is to minimize errors and maximiz…
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Design and Qualification of Single-Use Systems
The author provides a review of the concepts of design and qualification that apply to single-use systems.
By Jerold M. Martin
Single-use technologies (SUT) have made significant inroads in …
Article
Selection Guide Size Exclusion Chromatography Columns and Media
Size exclusion chromatography (SEC), also called Gel filtration (GF), separates molecules on the basis of differences in size as they pass through a SEC medium packed in a column. A variety of media…
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Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
Traditionally, column packing has been considered a bottleneck. By eliminating this concern, you can focus on the core process.
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Article
Antibody Production in Microbial Hosts
This is due to their larger radius of gyration than their glycosylated counterparts, and the crystal packing in aglycosylated structures may result in a “closed upper CH2 region” in their X-ray crysta…
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mAbs to Watch in 2016
By Randi Hernandez
Of the 45 new molecular entities and new therapeutic biological products approved by FDA in 2015, nine products were monoclonal antibodies (mAbs). And there may be many more o…
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Best Practices in Qualification of Single-Use Systems
FDA, Part 210 Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs; General.
6. FDA, Part 211 Current Good Manufacturing Practice for Finished Pharmaceuti…
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Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Optimization of each phase in a chromatographic cycle has a positive impact on productivity.
By Anna Grönberg
An important area of focus for the biopharma industry is the elucidation and dev…