Search results for "Digital"
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The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges.
By Kelvin H. Lee and Mark Lies
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Typical Purification Protocols to Obtain the Right Purity and Yield
Our free digital guide helps you effectively combine the main chromatography techniques to obtain a powerful purification protocol.
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Cytiva Invests $500 Million Over 5 Years to Expand Global Capacity
Other elements of the Uppsala investment include a capacity extension of Sephadex resin, which sets up additional facilities for in-house manufacturing, and the development of automation and digitaliz…
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Strategizing for Rapid Changeovers in Biologics Manufacturing
In particular, Stoll points out that automation and digital tools are enabling technologies for streamlining changeovers, such as via optimized scheduling of activities and electronic checks and instr…
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The Evolution of Supply Chain Security: Increasing Focus on Raw Material Variability
An increase in the development of biological and patient-specific drugs has also reinforced the demand for heightened raw material control.
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Mapping a Route for Cell and Gene Therapy Process Development
For gene therapies, advances in analytical techniques designed to address the needs of these complex products, such as digital droplet polymerase chain reaction, flow cytometry, and high-performance l…
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Using Software in Process Validation
Digital validation systems help to set a protocol that requires review, signoff, and signatures. The protocol is always checked and authenticated before the process can go into production. Software sy…
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Best Practices for Selecting a Top-Quality Cell Line
To detect low levels of CAR genes and microbial contaminants and precisely quantify CAR genes, Bio-Rad’s Droplet Digital PCR (ddPCR) technology is of increasing interest. The technology selectively am…
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Monitoring and Control of Inline Dilution Processes
We innovated on this proven technology by adding digital control to the pumps, adding a proprietary hydraulic design based on a model validated in cooperation with a university engineering team. We al…
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Tools and Processes for Mature and Emerging Therapies
A digital data exchange collaboration program between Cytiva and Amgen was developed to understand of the relationship between raw material variability and manufacturing process performance. The compa…