Search results for " recombinant" in Articles / App Notes
Article
Fundamentals of hydrophobic interaction chromatography
This technique separates proteins according to differences in their surface hydrophobicity, and is suitable for the purification of a large range of molecules:
* recombinant proteins and peptides…
Article
Optimization of a two-step purification method for bispecific antibodies
Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can bind two antigens, offering unique modes of action compared to monoclonal antibodies. New and i…
Article
What is process development?
Biopharma process development comprises the activities that help you create a series of steps to produce a biomolecule – a monoclonal antibody (mAb), recombinant protein, viral vector, or other produc…
Article
Need solutions for large-scale production of mRNA-based molecules?
mRNA therapeutics offer precise and individualized therapy and avoid manufacturing issues associated with recombinant proteins. Compared with current therapeutics, mRNA production is more cost-effecti…
Article
Trends in Outsourcing of Bioprocess Development
Growing numbers of conventional recombinant proteins and monoclonal antibodies, as well as next-generation molecules such as multispecifics, antibody-drug conjugates, and cell and gene therapies, are …
Article
Optimizing capture and polishing steps in an rAAV purification process
In this article, we show how we developed an efficient purification process for recombinant AAV (rAAV). The chromatography purification described includes affinity capture to maxi…
Article
Top Process Development Trends for 2021 and a Look into 2022
mRNA therapies offer manufacturing advantages over recombinant proteins, and they are more cost-effective and faster to produce than most therapeutics, not to mention their flexibility. This infograph…
Article
Maximum Output Starts with Optimized Upstream Processing
Significant growth in the development and manufacturing of biologics—from traditional recombinant proteins and monoclonal antibodies (mAbs) to advanced multispecifics, antibody-drug conjugates, viral …
Article
Cell-free Expression Systems Pose Cell Culture Alternative
During a short period of time, the system can make protein biologics with high efficiency with minimal by-products, and you don’t have to worry about proteolytic of recombinant protein caused by prote…
Article
Novavax Reports on Two Vaccine Efficacy Studies
Novavax announced on June 14, 2021, results from two studies of is recombinant nanoparticle protein-based COVID-19 vaccine; in a large study, the vaccine candidate demonstrated 90.4% efficacy overall …