Search results for " vaccine"
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Virus-like Particles as Therapeutic Moieties of the Future
Vaccine development
Traditional viral vaccines, which are based on inactivated or attenuated infectious virus, are difficult to produce and may cause adverse reactions in immunocompromised patient…
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Biopharma Manufacturers Respond to Ebola Crisis
Vaccine industry executives and biotech innovators joined the discussion about conducting effective and ethical clinical trials and ramping up production of promising vaccines and therapies. A main ai…
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Addressing the Challenges in Downstream Processing Today and Tomorrow
…elopment of antibody fragments, nanobodies, biosimilar protein therapeutics, conjugated proteins and vaccines, Fc-fusions, and nonantibody protein scaffolds. In addition to high cell density mammalia…
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Strategizing for Rapid Changeovers in Biologics Manufacturing
Through its Operation Warp Speed program for COVID-19 vaccine manufacturing, the US government is paying manufacturers and contract service providers to scale up the manufacture of specific vaccine ca…
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Enhancing Resins Addresses Purification Concerns
Resins have been seen as one tool that can address the purification needs of new COVID-19 vaccines as well as the existing challenges in the downstream processing of increasingly complex biologic moda…
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Microbiological Testing: Time is of the Essence
Alternative strategies for in-process release of vaccine batches were needed to accelerate production of flu vaccines, with the 14-day sterility test seen as a prime target for decreasing the turnarou…
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Unifying Continuous Biomanufacturing Operations
However, using perfusion to obtain high cell densities and increase output per bioreactor volume for the production of vaccines is of interest to researchers, too (7).
No need to scale: Eliminat…
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Ensuring the Biological Integrity of Raw Materials
Contamination of biologic drugs and vaccines by adventitious agents is extremely rare. However, when contamination incidents do occur, they can be costly in terms of time and resources.
In 2010, E…
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Pandemic Alters Policies and Practices for Drug Development and Regulation
The desperate need for new vaccines and therapies to tame the deadly COVID-19 virus required new policies and procedures for how biopharma companies select, test, and manufacture medical products—and …
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Top Process Development Trends for 2021 and a Look into 2022
…rus (AAV) production, process workflows and considerations for messenger RNA (mRNA) therapeutics and vaccines, and efficiencies in processes development.
As we move into 2022, let’s take a look …