Search results for "Biomanufacturing"
Poster
Resin selection to optimize the flexural strength of bioprocess film
Single-use bioprocess technology offers several advantages for manufacturing biopharmaceuticals, such as increased transportability of fluids throughout the bioprocess workflow and a greater diversi…
Article
Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
By Catherine Shaffer
Four biosimilars have been approved for the market by FDA as of February 2017, and more are in the pipeline. Now that biosimilars are here to stay, manufacturers are devel…
Article
Evaluating E&L Studies for Single-Use Systems
It is important to note that the case studies described in this paper are not to be intended in contrast with BPOG Standardized Extractables Testing Protocol for SUS in Biomanufacturing, which Merck a…
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
Increasing product titers in upstream cell culture processes pose challenges to downstream purification processes. For efficient operations, downstream purification needs to be able to handle high p…
Article
Modeling Bioreactor Performance
“Performance may be as much about the integration of the bioreactor in the overall biomanufacturing operation as it is about the physics of fluid dynamics. Analyzing with simulation scenarios, fluid p…
Article
Maximize resin usage with continuous bioprocessing
As such, there has been a growing interest in using continuous concepts also in biomanufacturing.
Periodic counter-current chromatography (PCC) is a multi-step approach to maximize the chromatog…
Article
Fed-batch supplements to boost cell culture performance
To increase the yield of a target protein, fed-batch culture is often employed in biomanufacturing processes. This application note demonstrates the enhanced performance of commonly used cell lines …
Article
Modular Manufacturing Platforms for Biologics
Cost of building a biomanufacturing module
Although some sources say that modular facilities require a modest upfront capital investment (3), others, such as consultant Emel, attest that a full mo…
Article
Implementation of Raw Material Control Strategies in the Manufacture of Single-Use Bioprocessing Containers
Ionizing radiation (gamma rays or electron beams), commonly used to sterilize single-use biomanufacturing equipment, can induce chemical and physical changes in the film, such as chain scission or cro…
Article
Challenges and Trends in Biopharma Facility Design
…f the benefits of single-use technologies, we offer the FlexFactory, which is a centrally-automated biomanufacturing platform.
Philips (Pall Life Sciences): The ‘ballroom’ concept is often define…