Search results for " cell"
Article
Principles of Cell Line Development
This free online course provides an overview of how cell line development plays a critical role in a biotherapeutic drug’s path to market. It also takes a closer look at where it fits int…
Article
Direct adaptation of adherent cell lines in classical media
Discover the options for direct adaptation of common adherent cell lines.
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Article
Cytiva Acquires Intermountain Life Sciences; Will Double Capacity for Buffers and Liquid Cell Culture Media
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Cytiva has acquired Intermountain Life Sciences, a manufacturer of high-purity water, buffers, and liquid cell culture media.
Article
Simple Fed-Batch Process Development for a Knockout Cell Line
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This workflow improved titers by 500% compared with Chinese hamster ovary cell culture in basal medium.
Article
Developing a Continuous Large-Scale Perfusion Cell Culture Process
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Perfusion processes enable continuous operation over extended periods of time by constantly providing fresh nutrients for the cells and simultaneously removing spent…
Article
Evaluation of Hek293 Cell Growth and Adenovirus Productivity in HyClone CDM4HEK293 Medium
This application note demonstrates growth and adenovirus productivity of HEK293 cells and explores the key factors involved in the optimization of cell culture performance and scalability.
Cli…
Article
Getting Ahead of the Game in Cell and Gene Therapy
Successes in the clinic have placed many cell and gene therapies on an accelerated route to market. But unless developers consider, at an early stage, how they might produce their product at scale, th…
Poster
Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
Here, they show that they can obtain culture media that successfully support perfusion cultures in bioreactors at cell-specific perfusion rates (CSPR) below 25 pL/cell/day. High productivities and fav…
Poster
Development of a chemically defined medium for virus vaccine production in a duck suspension cell line
A project was initiated to improve the production process for viral vaccines through the use of the EB66® cell line derived from duck embryonic stem cells and proprietary to Valneva. The primary goa…
Poster
One-step seed culture expansion from one vial of high-density cell bank to 2000 L production bioreactor
This application note describes how perfusion cell culturing can be used to reduce processing time, simplify operations, and maximize equipment utilization in seed culture expansion processes.