Search results for " resins" in Articles / App Notes

Article What If You Could Remove Your Antibody Aggregates Already in the Protein A Step?
Register for this free, online webinar >> In this study, the potential of Protein A chromatography to separate antibody monomer from HMW species was investigated. A design of experiments approach…

Article Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Mechanistic modeling is considered a part of smart process development, which is a collection of approaches to get better process outcomes and speed up process development. This week, Bioproce…

Article Next Generation Process Chromatography
…ve pressure while carrying out the same purification that are currently achieved with chromatography resins at slower rates. Other convective flow adsorbers have existed in bioprocessing for many yea…

Article Introducing Process Characterization Kit: New Tools for Gaining Deeper Chromatography Process Understanding
Study the potential impact of resin ligand density on process outcome with Process Characterization Kits. The kits provide critical insights on resin variation within the ligand density specificatio…

Article New Therapies Present Scaling Challenges
In the case of gene therapy, the resins would be specific to the capsid protein. The downstream purification aspect lends itself nicely to standard purification technology. Although there are many tec…

Article Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
A single-step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing three-step process. T…

Article Preclinical Evaluation of Product Related Impurities and Variants
Preclinical Evaluation of Product Related Impurities and Variants The approaches for sample preparation of preclinical evaluation of safety and efficacy are addressed taking into consideration the s…

Article Modeling and Miniaturization: Key Topics at Successful HTPD Conference
HTPD was mainly limited to 96-well plates filled with chromatography resins used for resin selection and initial screening of running condition. Since then, HTPD in chromatography applications has bee…

Article From Darwin to Recombinant Fc Multimers
…Buffer management via in-line conditioning systems, Radial flow chromatography, Novel chromatography resins, Ukraine plasma market, and Novel analytical assays based on Surface Plasmon Resonance. …

Article Unifying Continuous Biomanufacturing Operations
The success of a truly integrated continuous processing platform relies on the collaborative efforts of upstream and downstream specialists. By Randi Hernandez When human cells travel throug…

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