Search results for " resins" in Articles / App Notes
Article
Increasing Productivity in Hydrophobic Interaction Chromatography (HIC) Using Capto™ Resins
An application example is also presented in which aggregate removal results are compared using Capto™ Butyl ImpRes and Butyl Sepharose High Performance resins.
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Article
Cleaning Protein A Resins with 1 M NaOH
Historically, protein A resins have been less chemical resistant to high concentrations of sodium hydroxide (NaOH), the commonly used cleaning and sanitization agent in bioprocessing. In this applicat…
Article
Capacity and Performance of a Next Generation Protein A Chromatography Resin
Click here to read application note: Capacity and performance of MabSelect™ PrismA protein A chromatography resin
For more information, visit MabSelect Protein A resins
Article
Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
As the use of sodium hydroxide (NaOH) is considered standard in the bioprocessing industry, the impact of treatment of affinity resins with various concentrations of this cleaning agent is demonstrate…
Article
Guide for selecting affinity resins for mAbs, bsAbs, and antibody fragments
Development of antibody-derived molecules are increasing. Today, molecules such as bispecific antibody (bsAb) and antibody fragments such as Fab, scFv, and VHH are seen in labs all over the w…
Article
Alkaline stability of Fc and VH3 binding in protein A resins
We evaluated NaOH incubation and the effect of performed CIP cycles for two established protein A resins on the market.
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Article
Selection Guide: Columns and Resins for Antibody Purification and Immunoprecipitation
Download the latest version of the selection guide Columns and Resins for Antibody Purification and Immunoprecipitation to help you select the most suitable affinity column for purifying your antibody…
Article
Maximize resin usage with continuous bioprocessing
Continuous processing has proved a very successful model in many industries. As such, there has been a growing interest in using continuous concepts also in biomanufacturing.
Periodic counter-…
Article
Buffer optimization for separation of bsAb in a capture step using MabSelect™ VL resin
Protein L resins bind to kappa light chain and are often used to purify antibody fragments such as dAbs and Fabs — but they can also be used to remove product-related impurities from bispecif…
Article
Process development using a nonaffinity method vs Cytiva™ Protein Select™ resin
In this study, we compared two approaches for purifying a recombinant protein that does not have an affinity binding partner.
The first method is using nonaffinity chromatography steps (AI…