Search results for "automation" in Articles / App Notes
Article
The Importance of Process Intensification and PAT for Achieving Real-Time Release
Aspects of automation, miniaturization, and multi-attribute methods have also been explored.
This collective work has begun to establish the feasibili…
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Single-use Bioreactors Have Reached the Big Time
Automation and process control, both of which are essential to enabling consistent and reliable biomanufacturing, have improved greatly for single-use bioreactors as well. “Historically, single-use te…
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Improving Process-Scale Chromatography
The development of new resin chemistries including enhancements to Protein A for monoclonal antibody (mAb) capture, increasing use of automation, implementation of single-use technologies, and explora…
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
Sterile filtration will remain the standard, but with more automation
The fundamental issue with sterile viral-vector manufacturing is the need to keep out or remove undesired organisms such as bac…
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Single-Use Technologies Prove Effective for Viral Vector Process Development
Rocking bioreactors, fixed-bed bioreactors, and stirred bioreactors do enable aseptic, closed operations and are amenable to automation. They are also designed to increase cell-culture density while m…
Article
Best Practices for Selecting a Top-Quality Cell Line
Leveraging automation
Catalent is leveraging automation to create high-quality cell lines and timelines. The company combines its proprietary GPEx cell-line development technology with the B…
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Multistep Protein Purification: Gain Time and Consistency
In this webinar, "Gain Time and Add Consistency with Automated Multistep Protein Purification," the presenters discussed the benefits of automation, how to set up an automated purification protocol,…
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Microbiological Testing: Time is of the Essence
Some methods are still culture-based, but with automation to help accelerate the process. Others involve completely new testing technologies.
“Some automated RMMs use a culture phase coupled with a…
Article
Platform Approach Speeds Process Development
The platform includes vector design, cell line engineering, high-throughput screening by automation, systematic design of experiment (DoE)-based approaches for media and cell-culture process developme…
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Tools for Continuous Bioprocessing Development
In addition to optical pH and DO sensors, the system combines miniaturized stirred tanks with a pipetting robot and automated feed pumps, greatly improving automation of the fermentation process. By u…