Search results for "biosimilar"
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The Future of Biopharma
The current situation in the biopharmaceutical industry is exciting enough, with biosimilars, new technologies, personalized medicines, and opportunities in emerging markets. The industry, however, be…
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Best Practices for Selecting a Top-Quality Cell Line
This issue is particularly important for biosimilars, because the glycosylation patterns of biosimilars must meet biosimilarity specifications when compared to the innovator drugs, which can only be a…
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Report from India
Enhanced focus on over-the-counter products, vaccines, and biosimilars would start gaining importance in overall business strategies. Companies will look at in-licensing initiatives, comarketing, and …
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QbD and PAT in Upstream and Downstream Processing
This also holds for biosimilar products.
McKnight (Genentech): CQAs are defined for the product, not identified as part of upstream or downstream portions of the manufacturing process. There are…
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Determining and Optimizing Dynamic Binding Capacity
Dynamic binding capacity (DBC) indicates the quantity of a specific biomolecule that can be bound during a chromatography purification step under a specific set of process conditions. Determ…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
I also continue to be surprised by the magnitude of efforts in follow-on biopharmaceuticals, particularly biosimilars. BioPlan's Biosimilar/Biobetters Pipeline Directory is now tracking over 1,000 bio…
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Evaluating the Use of Continuous Chromatography
Continuous processes continue to advance in bioprocessing. In downstream processing, continuous chromatography is gaining traction in the purification of protein therapeutics. As the biopharma…
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Webinar: Intensifying downstream bioprocessing with continuous technologies
Webinar on June 20, 2024
Significant operational improvements can be achieved by intensified continuous processes compared to standard batch processes.
In this webinar we will explor…
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Alternative solutions to separate AAV full and empty capsids using anion exchange
Adeno-associated virus (AAV) is the main vector for gene therapy and there is need for scalable, cost-efficient, and robust chromatography-based purification. Key for a successful process are …
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A Closer Look at Affinity Ligands
Affinity ligands play an exciting role in the ever-growing sphere of downstream processing. In speaking with BioPharm International®, Phillip Elliott, PhD, associate director of Process Development,…