Search results for "Workflow"
Article
See a chromatography modeling software in action
The typical mechanistic chromatography modeling workflow is an interplay of the tools that you currently use in the lab and the modeling software (Fig 2).
Fig 1. Mechanistic modeling creates…
Article
Webinar: Optimizing a HIC step with HTPD
This workflow includes the use of high-throughput process development (HTPD) plates to facilitate the choice of resin and initial conditions for column chromatography, and a design of experiments (DoE…
Article
Simplify-bioreactor scale up and scale down: applications and tools
A well-designed scaling strategy, workflows, and easy-to-use tools will facilitate the scaling exercise. In this article we present the theory for bioreactor scaling and propose a workflow to scale th…
Webcast
A route to deeper process understanding-Studying resin variability using a Process Characterization
This webinar illustrates a cation exchange chromatography process development workflow to assess the potential effect of ligand density variability on product quality and process performance using a P…
Article
Traceability in Western Blot Imaging: Considerations for GxP
In this article, we discuss what implications these regulations have on workflows using gel and blot imaging systems to capture, analyze, and document images. We cover what to consider, what to look o…
Article
Process Development: 2020 Reflections and 2021 Possibilities
… chimeric antigen receptor (CAR) T-cell therapy and gene therapy applications, by creating a modern workflow that reduces timely manual labor, was also highly relevant in 2020.
Improving Process …
Article
On-Demand Webinar: A Route to Deeper Process Understanding—Studying Resin Variability Using a Process Characterization Kit
This webinar illustrates a cation exchange chromatography process development workflow to assess the effect of ligand density variability on product quality and process performance using a Process Cha…
Article
2019’s Top Bioprocessing Trends and What to Expect in 2020
FDA approvals announced during the year for cell and gene therapies prompted the need to consider manufacturing facility designs specific to cell and gene therapy workflows, as well as the need to exp…
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
The workflows of a cell therapy or a gene therapy differ from each other and from those of therapeutic antibodies, so the design and layout of the manufacturing facility must take these workflows into…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
“Single-use systems are an attractive option for emerging markets, not only in chromatography but all along the production workflow,” says Young, who sees this as the technology’s most important contr…