Search results for " modeling" in Articles / App Notes
Article
The Affordable Care Act's Impact on Innovation in Biopharma
The biopharmaceutical industry contemplates product innovation within the changing landscape of healthcare.
The Affordable Care Act (ACA) has elicited intense national debate and sent biopharm…
Article
Preclinical Evaluation of Product Related Impurities and Variants
Fourth, empirical modeling of the resulting data was performed to correlate each of the charged variant to biological activity. Once charge variants that were seen to have statistically significant im…
Article
Report from the 12th Plasma Product Biotechnology Forum
Mechanistic Modeling
A key role for the conference is of course to present and share how modern technologies can improve efficiency and robustness of plasma fractionation. Takeda’s Paul Sylvain…
Article
Maximum Output Starts with Optimized Upstream Processing
Samsung, for example, is leveraging automation, ultra scale-down modeling in microreactors, in-silico and predictive modeling including metabolomics, and mobile apps for company-wide data visibility t…
Article
QbD Improves Cell-Culture Process Control
However, using a quality-by-design (QbD) approach that employs predictive modeling can improve the quality of end product as well as the efficiency of the bioprocess.
Real-time quality control
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Article
Being Thorough When Transferring Technology
This can be met with qualified scale-down models or modeling. Successful scale-up that matches predicted behavior demonstrates good process understanding. This can help in justifying fewer as opposed …
Article
Managing Biomanufacturing Capacity Expectations
Capacity for complex therapeutics is becoming increasingly difficult to predict.
By Randi Hernandez
Demand for any given new product is typically only known after significant investments h…
Article
Advanced Technologies Facilitate Scale-up and Technology Transfer
Scale-down modeling for successful scale-up and tech transfer
One of the benefits of the use of smaller production facilities is a reduction in the scale-up factor for many biopharmaceutical proce…
Article
Modular Manufacturing Platforms for Biologics
May 01, 2015
By Randi Hernandez
BioPharm International
Volume 28, Issue 5
It should come as no surprise that the good design principles governing the execution of pharmaceutical manu…
Article
Viral Clearance Challenges in Bioprocessing
Challenges remain for virus removal and validation.
Nov 1, 2014
By: Cynthia Challener, PhD
BioPharm International
Volume 11, Issue 27, pp. 42-44
Removal and inactivation of adventitio…