Search results for " reproducibility"
Article
Technology Innovations Improve Process Chromatography Performance
The performance reproducibility in column packing, which is essential for ensuring consistent scale-up, can accelerate technology implementation in manufacturing, says Hemanth Kaligotla, chromatograph…
Article
Improving Upstream Predictability
The structured fixed-bed contributes to even cell distributions throughout the bed matrix, which improves productivity and reproducibility relative to other commercial systems, says Chatel, while the …
Article
How to Pack Lab-Scale Columns
Get reproducible chromatography performance through a well-packed column. See below for resources and tips for how to usefully pack lab-scale columns.
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Article
Mapping a Route for Cell and Gene Therapy Process Development
While cell and gene therapies differ in many ways, some of the best practices for process development and validation are similar.
By Cynthia A. Challener
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Article
The Evolving Role of Starting Materials in Cell and Gene Therapy
The Evolving Role of Starting Materials in Cell and Gene Therapy
Accelerated approval pathways and growing demand for cell and gene therapies are putting pressure on providers of cellular starting m…
Article
Best Practices for Selecting a Top-Quality Cell Line
Irina Shi - Stock.Adobe.com
Leveraging automation and a step-by-step approach are keys to success.
By Cynthia A. Challener
Cell lines determine the performanc…
Article
Moving PAT from Concept to Reality
The learning curve for process analytical technology has slowed widespread adoption.
By Cynthia A. Challener
alexlmx a- Stock.Adobe.com
Process analytical technology (P…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Hindrance or help?
Many disposable chromatography columns meet cGMP and industry standards, and also offer reproducibility, scalability, speed, ease-of-use, and operational safety.
However, chr…
Article
New HiScale™ 10/40 for Scale-Down Studies
Cytiva is pleased to announced the new HiScale™ 10/40.
HiScale 10/40 column is especially suitable for scale-down studies used in, for example, viral clearance evaluation in downstream processing. …
Article
Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
SPR has also shown greater precision and reproducibility than the traditional cell-based assays such as ADCC and CDC.
SPR applications are not only limited to ligand–receptor interacti…