Search results for "bioreactor"
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Biopharma Advances Demand Specialized Expertise
Single-use disposable bioreactors and similar single-use bioprocess equipment minimize plant downtime, which is traditionally required for line clearance and product changeover. The complexity of prod…
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Continuous Chromatography: Trends, Definitions and Approaches
Obviously, prevention of bioreactor contamination is of paramount importance if the reactor is operated in perfusion mode and is connected to a continuous chromatography system, but this can be realiz…
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Technologies and Practices Must Evolve to Meet Demand
Cell-culture products, bioreactors, filtration, chromatography columns, and centrifugation received “excellent” grades from more than 24% of those surveyed. More than 10% of the respondents, however, …
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Optimizing Resin Performance with Disposable Chromatography Solutions
We are definitely seeing growth as well as demand for larger columns that are suitable for use with 1000-L and 2000-L bioreactors. In just a couple of years this line is generating multimillion dollar…
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Single-Use and Continuous Processing Technologies Change Facility Design
With no waiting for cell growth and cell-culture bioreactors continuously operating, columns can be smaller than when they need to handle whole fermenter volumes at one time. Ultimately, the whole fac…
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2014 Manufacturing Trends and Outlook
Regulatory issues, costs, analytics, and inadequate bioreactor volumes were other challenges (see Table I).
Process analytical technologies
More than half of the responden…
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Selected courses from cell culture and downstream process development to scale-up and manufacturing
Examples of available free of charge eLearning courses:
What is quality by design (QbD)?
Principles of cell line development
Bioreactor scaling
Filtration in bioprocessin…
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Innovations in Perfusion Bioprocessing
In this study, we present a method for deriving perfusion culture media by leveraging existing fed-batch media and feeds.
Furthermore, we illustrate the successful transfer of the develop…
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Advances in Sterilization Technologies for Overcoming Viral-Vector Manufacturing Challenges
“For a 50-L bioreactor run, the intermediate downstream processing volumes can already be below 2 L after the capture steps, but single-use mixers currently on the market start at 50 L,” she explains.…
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Instructional Videos for Bioprocess Equipment
Cytiva offers free on-demand instructional videos that will help you with operating bioreactors, chromatography and filtration systems, including flow kit installation on single-use systems. Modules a…