Search results for " scalability"
Article
Top Challenges to Overcome When Developing AAV Processes: Part 1 of 2
Topics covered include:
1:00 – Two main challenges for upstream AAV process development, including which development platform to use and scalability
3:09 – Parameters evaluated for AAV p…
Article
Cytiva Advances Fiber Chromatography Technology with New Launch
The launch of HiScreen Fibro PrismA, the company’s newest product for early mAb purification process development strengthens Cytiva’s new fiber-based Protein A platform.
On Jan. 27, 2021, Cyti…
Article
Remote Monitoring and Big Data Advance Upstream Automation
“Hardware advances give the opportunity for higher cell densities and improved scalability, software enables the flexible use of these systems and speeds their deployment, and sensors and analytics he…
Article
Process Development: 2020 Reflections and 2021 Possibilities
The challenges posed by the COVID-19 pandemic in 2020 brought about many unprecedented lessons and promising developments in the biopharmaceutical industry. Last year in particular reenforced the ne…
Article
Tapas & TECH Talks: Panel Discussion with Cytiva/IQVIA
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When developing a new therapy, it is more important than ever to have the future in mind from the outset. The choices you make at each step can set you up for …
Article
Scaling a mAb Production Process to Xcellerex Bioreactors
This article discusses moving a monoclonal antibody (mAb) production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Article
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
Biomanufacturing: Demand for Continuous Bioprocessing Increasing
But are innovations sufficient to increase adoption? CMOs are demanding better continuous bioprocessing options. …
Article
Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
Article
Evaluation of Hek293 Cell Growth and Adenovirus Productivity in HyClone CDM4HEK293 Medium
This application note demonstrates growth and adenovirus productivity of HEK293 cells and explores the key factors involved in the optimization of cell culture performance and scalability.
Cli…
Article
Improving Upstream Predictability
Pall has also developed modeling and scalability tools for its iCellis and Allegro bioreactor lines and is integrating bioreactors with Aber Instruments’ Futura biomass probe for continuous cell bioma…