Search results for " development" in Articles / App Notes
Article
A Look into Biologic Scale-Up Strategies
Optimizing cell-culture processes for monoclonal antibody (mAb) production is a key factor in scaling up manufacturing to commercial levels. To maximize cell-culture output, strategy is requir…
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Xcellerex™ X-platform bioreactor live virtual demo
We designed Xcellerex™ X-platform bioreactors to meet your process needs today and in the future. Whether in pilot or cGMP facilities, the modular and application-based approach improves cell …
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How to Use Multiwell Plates With Manual Operation
During process development, aspects like robustness, scalability, and GMP production come into play. FDA initiatives such as quality by design (QbD) put demands on better process understan…
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Current Trends in Host Cell Protein Detection for Biologics Manufacturing
Commonly accepted HCP analytical methods, the challenges of HCP assay, and recommendations on what can easily be accomplished in-house and when it may be better to outsource.
Read more here…
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See a chromatography modeling software in action
Mechanistic models use computer simulations to decrease the number of experiments you need during process development.
The simulations are based on known physiochemical phenomena involved in ch…
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Chromatography innovations for the diverse antibody pipeline
To support development of new therapeutic possibilities, manufacturing and process development technologies must also evolve. For antibody variants, platform purification protocols for conve…
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Emerging biopharma: progressing a biologic drug to market
There are many pitfalls in the road to developing and bringing a new therapy to market. Understanding some of these areas and being prepared to make the right decisions at the right ti…
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Implementing Inline Conditioning to Advance Process Intensification
This week, Bioprocess Development Forum spoke with Filippo Bertoli, Senior Associate Scientist, Séamus McHugh Operations Manager, Joanne Sheehy Staff Manufacturing Process Specialist, Sean Coomey Prin…
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Improving the Oligonucleotide Synthesis Experience
Addressing this challenge was one of Cytiva’s main goals when we set out to develop a system for small-scale synthesis and process development.
>>> Watch the presentation
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Optimization of a Two-Step Purification Method for Bispecific Antibodies
Alligator Bioscience AB develops antibody-based pharmaceuticals for cancer treatment, specializing in mono- and bispecific antibodies for tumor-directed immunotherapies. Alligator and Cytiva devel…