Search results for " manufacturing" in Articles / App Notes
Article
Current Techniques and Challenges Presented in Scaling Between Bioreactors
In smaller companies with fewer projects the PD team takes a large responsibility and follows the process for clinical manufacturing. On the other hand, in larger organizations with broad portfolio of…
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A better way to purify small drug volumes
Viral vectors: demand is high and getting higher. But purifying viral vectors with methods optimized for other products can affect yield, purity, and cross-contamination.
How does the …
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Assessing leachables risk over a complete single-use, mAb process
Single-use systems (SUS) in biopharmaceutical manufacturing give advantages such as improved flexibility and plant efficiency, but also raise concern for compounds leaching from the pol…
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Cytiva expanding US operations
Cytiva, a global life sciences leader, is investing in additional resins manufacturing operations outside of Sweden, for the first time in the company’s history, with the acquisition of a …
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mRNA: the messenger
Exploring the mRNA manufacturing universe? Proceed with confidence with some top tips from our scientists on mRNA synthesis and production. Watch the video to learn more about keeping the environ…
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Developing a Robust Bioprocess Using Mechanistic Models
The robustness of the manufacturing process has to be validated in order to bring a new biological drug to market.
Regulatory agencies such as the Food and Drug Administration (FDA) and Euro…
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Simulating chromatography processes in the growing molecular diversity
Depending on the specific molecule and the manufacturing process used, different modeling strategies may be required.
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In silico Approaches towards Automated Biomanufacturing
As part of manufacturing science and technology (MSAT), mechanistic modeling can be used to support several activities in biopharmaceutical production, including process transfer activities, in silico…
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A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
Perfusion continues to be one such operating mode which lends itself to adding benefit at the manufacturing scale while adding complexity to the small-scale approach.
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Increasing mRNA Capabilities and Capacity for Growing Market Needs
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The success of the mRNA vaccine market is fueling high demand for mRNA, resulting in a critical need to address the manufacturing bottlenecks.