Search results for " manufacturing" in Articles / App Notes
Article
Modeling Bioreactor Performance
Model effectiveness is determined by the quality and composition of the data inputs.
By Cynthia A. Challener
Bioreactor design, including the geometry of the tank and impeller and the locati…
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High-Throughput Process Development Handbook
Efficient development of the manufacturing process is a crucial component of the overall project plan. However, screening optimal process conditions can be time-consuming and tedious. In addition, ste…
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A Second Modular Biopharma Facility Opens: KUBio in Hangzhou
The center will also include filling and packaging lines providing end-to-end manufacturing capability in a single facility.
Read more here
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Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
The goal for biopharmaceutical manufacturers is to develop a process that will deliver material for clinical trials quickly and smoothly, achieve success in these trials, and scale up to commercial …
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Optimization of Protein Expression in Escherichia Coli
Conclusion
Choosing the best expression system depends largely on the target protein and the scale of manufacturing. There are many factors that can be optimized. This article merely touches on a n…
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DoE Provides Benefits, but Preparation Is Necessary
LaBrenz, scientific director, pharmaceutical development and manufacturing sciences with Janssen Research & Development. At the same time, DoE results depend on the selected critical parameters and th…
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Challenges of Protein Aggregation During Purification
The technology was developed at the University of Colorado and is currently marketed by BaroFold under the name Pressure Enabled Protein Manufacturing (PreEMT) technology. In January 2013 and November…
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Evaluating Design Margin, Edge of Failure and Process
Two additional analyses are required to assure the chemistry, manufacturing, and control (CMC) team and associated health authorities all set points are safe with low out-of-specification (OOS) rates …
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Quality Considerations for Using AI in Bio/Pharma
But does the regulated nature of bio/pharmaceutical development, manufacturing, and commercialization serve up unique challenges for incorporating AI into processes? According to Siegfried Schmitt, vi…
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Introducing the VH3 ligand ELISA kit
Ensuring the safety and efficacy of antibody-based therapeutics is crucial in biotherapeutic manufacturing. Accurate testing for ligand leakage from affinity resins is a key part of this proce…