Search results for " affinity" in Articles / App Notes
Article
Purifying Tagged Proteins: Learn the Basics
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What is tagged protein purification? When and why should you use it? Learn the basics in our quick guide to tagged protein purification.
Article
Updating Viral Clearance for New Biologic Modalities
In downstream processing, chromatographic separations leverage interactions through affinity, charge, or hydrophobicity, says Verlenden. Improvements in chromatographic separations designed to maximiz…
Article
Testa Challenge 2020 Attracts Leading International Bioprocessing Innovators
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Six bioprocessing innovators have successfully completed the inaugural Testa Challenge 2020. Held over an intensive week in the Testa Center located at Cytiva´s Uppsala…
Article
Platform for Purification of VHH-type Antibody Fragments
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Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…
Article
DiPIA online
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Biacore surface plasmon resonance application specialists are eager to share their experience in assay design, validation, and data evaluation.
Article
Gene Therapies Push Viral Vector Production
Other innovations, such as affinity ligands for specific AAV serotypes are being developed for use with these technologies to further enhance the resolution of the capture step. A major challenge rema…
Article
2019’s Top Bioprocessing Trends and What to Expect in 2020
2019 proved to be an exciting year for biopharmaceutical developers and process engineers, filled with both advancements and lessons. Considering how far the industry has come, what direction will 2…
Article
New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
For example, one unmet user need is the lack of affinity and ionexchange chromatography beads that are sufficiently cost-effective to be classified as single-use. These process steps continue to be th…
Article
Biopharmaceutical Process Development: 2018 Lessons and 2019 Predictions
…ey to More Effective Vaccines
• Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
• Optimization of Fed‑Batch Culture Condit…