Search results for " continuous" in Articles / App Notes
Article
Risk Assessment and Mitigation in Biopharmaceutical Manufacturing
Risk management should be a continuous process to be effective.
Using the same risk management tool and a standardized process for QRM, and all other business continuity risks, allows employees to…
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Sterilization Trends for Single-Use Consumables
Single-use (SU) technologies increasingly find use today at all phases of the drug development cycle from preclinical to commercial manufacturing. As the biopharmaceutical market continues to …
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Genetic Vaccine Platforms Demonstrate Their Potential
In a pandemic, genetic vaccines offer several advantages over traditional approaches.
By Cynthia A. Challener
For a vaccine to be effective, the components of the disease o…
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Updating Viral Clearance for New Biologic Modalities
Another area of intense product development is in systems that will support intensified and continuous in-line viral inactivation, Verlenden says. “As we look to develop more rapid manufacturing proce…
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Improving Upstream Predictability
“We’re seeing shrinking process footprints through continuous integration and connection of upstream and downstream processing,” he says.
The end result will be lower capital investment cost…
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Cell-Culture Advances Test Bioreactor Performance Models
Continuous considerations
In the past, continuous processing in perfusion mode was generally limited to cell-culture processes involving sensitive products that degrade under conventional batch …
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Single-Use for Downstream Chromatography: Benefit or Hindrance?
“[Adopting] single-use systems gives manufacturers the potential to move from a batch-based approach to something approaching a connected continuous process. It will be possible to minimize the number…
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The Outlook for CMO Outsourcing in 2019
By Eric Langer and Ronald A. Rader
Biopharmaceutical industry-related indicators and trends are supporting continued incremental increases in outsourcing of pre- and commercial AP…
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Process Development: What May Lie Ahead in 2018?
2018 is shaping up to be an interesting year in the world of biopharmaceuticals. What have 2017 developments taught us, and what may lie ahead for biopharmaceutical drug developers and process engin…
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Process Chromatography Selection for Downstream Processing Applications
Levison (Pall): With the introduction of continuous chromatography and optimization of flow through approaches to membrane chromatography, novel ligands, and base matrices may gain broader application…