Search results for " drug"
Article
Pulling Out All the Stops in mAb Manufacturing
While the biopharma industry is pushing the barriers with antibody development, it must also contend with contemporary challenges in bulk monoclonal antibody (mAb) manufacturing. The need for…
Article
Pushing the Barriers in Next-Gen Antibody Development
Continued development of new and next-generation antibodies is spurred by the increasing demand for more effective and custom-tailored biologic therapies. In particular, bispecific antibodi…
Article
eBook: Purification of Antibody Therapeutics - Approach for Diversified Pipeline
Today, we see multispecific and bispecific antibodies, antibody fragments, and antibody drug conjugates in the development pipeline. Manufacturing platform approaches conveniently used for many tradit…
Article
Visualize the Xcellerex™ X-platform bioreactors in 3D
Bioreactors are integral to the manufacture of protein-based drugs, especially monoclonal antibodies. Xcellerex™ X-platform bioreactors from Cytiva are designed to meet process needs of today …
Article
Optimization of a two-step purification method for bispecific antibodies
The company is active in the early stages of drug development, from early concepts to clinical phase II studies.
This presentation shows the results from Cytiva collaborating with Alligator to deve…
Article
Top Process Development Trends for 2022 and a Look into 2023
FDA approved 37 drugs in 2022, within the normal range for the past decade or so. The European Medicines Agency (EMA) was even more successful—approving a record 55 therapies. More than half of thes…
Article
Reducing the Risk of RNAse Contamination in mRNA Production
As drug and vaccine manufacturers work to optimize mRNA production processes, one hurdle to overcome is mRNA’s susceptibility to breakdown by ribonuclease (RNase) enzymes introduced during p…
Article
mRNA: The messenger - LNP formulation
Join us for part 5 of mRNA: the messenger, where we discuss key considerations for the formulation of lipid nanoparticles (LNPs) for mRNA drug delivery, including mixing, encapsulation, polishing and …
Webcast
e-learning: Principles of Cell Line Development
This free online course provides an overview of how cell line development plays a critical role in a biotherapeutic drug’s path to market.
Article
Establishing a Robust Workflow to Identify GOCHO™ Clones
Cell line development is typically on the critical path of drug development. It’s a complex, labor intensive, and multistep process. Our new cell line development platform uses the GOCHO™…