Search results for " drug" in Articles / App Notes
Article
eBook: Purification of Antibody Therapeutics - Approach for Diversified Pipeline
Today, we see multispecific and bispecific antibodies, antibody fragments, and antibody drug conjugates in the development pipeline. Manufacturing platform approaches conveniently used for many tradit…
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Visualize the Xcellerex™ X-platform bioreactors in 3D
Bioreactors are integral to the manufacture of protein-based drugs, especially monoclonal antibodies. Xcellerex™ X-platform bioreactors from Cytiva are designed to meet process needs of today …
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Optimization of a two-step purification method for bispecific antibodies
The company is active in the early stages of drug development, from early concepts to clinical phase II studies.
This presentation shows the results from Cytiva collaborating with Alligator to deve…
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Top Process Development Trends for 2022 and a Look into 2023
FDA approved 37 drugs in 2022, within the normal range for the past decade or so. The European Medicines Agency (EMA) was even more successful—approving a record 55 therapies. More than half of thes…
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Reducing the Risk of RNAse Contamination in mRNA Production
As drug and vaccine manufacturers work to optimize mRNA production processes, one hurdle to overcome is mRNA’s susceptibility to breakdown by ribonuclease (RNase) enzymes introduced during p…
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mRNA: The messenger - LNP formulation
Join us for part 5 of mRNA: the messenger, where we discuss key considerations for the formulation of lipid nanoparticles (LNPs) for mRNA drug delivery, including mixing, encapsulation, polishing and …
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Establishing a Robust Workflow to Identify GOCHO™ Clones
Cell line development is typically on the critical path of drug development. It’s a complex, labor intensive, and multistep process. Our new cell line development platform uses the GOCHO™…
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What’s in your media? How costly is variability of cell culture media to your manufacturing process?
For example, the small amounts of metal like zinc may influence the glycosylation pattern on a monoclonal antibody— which translates directly into the drug efficiency and effectiveness. It matters in …
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Join DiPIA 2022
Don’t miss out on latest applications and developments in biophysical characterization, join our two half-days conference where researchers will present their work using surface plasmon r…
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Do Modeling and Simulation Tools Really Benefit the Biosimilar Industry?
The business impact of modeling and simulation tools is not well understood and requires clarification of their benefits to drug development.
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