Search results for "host"
Article
Regulatory Challenges in the QbD Paradigm
The products can be produced from the same host or from different hosts but must be from well characterized cell lines (e.g., ICH Q5A) and not highly toxic or potent. The second case is the site trans…
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Reviewing the Importance of Biosimilarity and Interchangeability
Stamm also points out that analytical methods should be established to identify and quantify residual host cell proteins to ensure they are within acceptable limits because their presence could impact…
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You are invited to attend DiPIA 2024
DiPIA, or Developments in Protein Interaction Analysis, is a global scientific conference hosted by Cytiva. We bring peers together from across the industry to share best practices, research, and new …
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How to program, run and evaluate a design of experiments (DoE)
An application example showcases how to optimize an antibody purification for low dimer-and-aggregate and host cell proteins (HCPs) content while achieving best possible yields.
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Establishing a Robust Workflow to Identify High-Performing GOCHO™ Clones
Our cell line development platform uses the GOCHO™ host cell line to minimize the risk and timeline to develop high-performing clones suitable for manufacturing.
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Establishing a Robust Workflow to Identify GOCHO™ Clones
Our new cell line development platform uses the GOCHO™ host cell line to minimize the risk and timeline to develop high-performing clones suitable for manufacturing.
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Join the Plasma Product Biotechnology Meeting
The conference will host participants from all major plasma fractionator companies and additionally this year we have the privilege to welcome Dr Dorothy Scott from FDA and Branch Chief of the Plasma …
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Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
Mammalians cells, especially HEK293, are popular hosts; however, insect cells are also used. These originate as tissue and thus favor growing in adherence but are also being adapted to grow in suspens…
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Innovative Chromatography Resins Can Improve Purity and Quality
He concluded that conventional multi-step DSP development bears the increased risk of commercial viability, where yield, impurity levels (such as host cell proteins or product-related impurities) or o…
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Manage HCPs and Enhance Your Route to Market
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Host cell protein (HCP) management is critical to biologics development—and getting it wrong could delay your development cycle. Learn how the right HCP strategy can enhance…