Search results for " sanitization" in Articles / App Notes
Article
Sterilization Trends for Single-Use Consumables
Diffuse Security Threats: Technologies for Mail Sanitization Exist, but Challenges Remain. Report to Congressional Requesters, April 2002. https://www.gao.gov/assets/gao-02-365.pdf
Comben, M. V…
Article
A Closer Look at Affinity Ligands
As an example, much engineering has recently gone into modifying the Protein A ligand to ensure it can withstand the stringent cleaning and sanitization procedures required for use in a pharmaceutical…
Article
The Importance of Partnering for Bioanalytical Studies
The Importance of Partnering for Bioanalytical Studies
Yakobchuk Olena/Stock.Adobe.com
Bioanalytical studies are an important aspect of biologic drug development that may necessitate…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Single-use technology is gaining ground in downstream bioprocessing, but challenges stall further adoption.
By Feliza Mirasol
ARTMOIS/STOCK.ADOBE.COM
Biopharmaceutical manufactu…
Article
A Look at the Affinity Chromatography Landscape
Protein A is the most sensitive resin to cleaning-in-place and sanitization processes, and one key issue has been the development of more robust versions that can withstand high pH washes to prevent b…
Article
Chromatography Scale-Up: Don’t Get Tied Down by Bed Height
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When scaling, you can make better use of existing chromatography columns while avoiding overcapacity.
Keeping a constant residence time is a well-est…
Article
How to Address Bioburden Challenges: Insights and Tips
Another important area where suppliers can contribute is sanitization and storage procedures for protein A chromatography resins, which are widely used to purify mAbs.
Learn more about insights an…
Article
Bioburden Control in the Biopharmaceutical Industry
Protecting against microbiological contamination over the whole manufacturing process grows increasingly important.
By Mostafa Eissa
The biopharmaceutical industry has witn…
Article
Process Chromatography: Continuous Optimization
Current protein A resins are also exposed to feeds with high concentrations of cell-culture nutrients yet are more sensitive to the high concentrations of sodium hydroxide needed for cleaning and sani…
Article
Ensuring the Biological Integrity of Raw Materials
By Catherine Shaffer
Contamination with microbes, mycoplasma, viruses, and other adventitious agents can be a significant problem in biopharmaceutical manufacturing. Although contamination can o…