Search results for " future" in Articles / App Notes

Article Addressing the Challenges in Downstream Processing Today and Tomorrow
In the future, mAbs may represent a smaller percentage of the pipeline as portfolios concentrate more on development of antibody fragments, nanobodies, biosimilar protein therapeutics, conjugated prot…

Article Setting Up Bioprocessing Systems for Digital Transformation
“Once the organization confirms that units are consistently performing as expected, more advanced real-time modeling and simulation predicts how production will behave in the future.” Lenich expla…

Article Genetic Vaccine Platforms Demonstrate Their Potential
…ng vaccine hesitancy, will be required for efficient and broad acceptance of genetic vaccines in the future for a larger set of pathogens outside the current COVID-19 pandemic,” she continues.  …

Article Design Considerations for a Commercial Cell and Gene Therapy Facility
In addition, material, personnel, and waste flows require special attention for the current design and in support of future expansion needs. “As a contract development and manufacturing organiza…

Article Fifteen Years of Progress: Biopharmaceutical Industry Survey Results
The advances in upstream titers are reflected in survey responses regarding the top areas industry needs to address to avoid future capacity constraints, with developing better continuous and better o…

Article A Risk-Based Genetic Characterization Strategy for Recombinant CHO Cell Lines Used for Clinical and Commercial Applications
The established assessment methods will be applied to characterize the expression construct needed for future MAA. The tested limit for in vitro cell age will be used to propose the commercial manufac…

Article Implementing Inline Conditioning to Advance Process Intensification
…ion from a classical buffer make up system to a preparation of concentrated stocks with platform and future products in mind. This required integrating new processes like IC calculations, quality man…

Article Using Digital Twins to Model Process Chromatography
Future use of digital twins   BioPharm: What do you predict for how digital twins will be used in biopharma in the future? Whitelock (GoSilico): Over the past few years, we have seen great ent…

Article Process Development: 2020 Reflections and 2021 Possibilities
Tobias Hahn, PhD, co-founder and CEO of GoSilico, took time to discuss the current benefits observed using mechanistic modeling for many applications in bioprocess development, as well as its future i…

Article Strategizing for Rapid Changeovers in Biologics Manufacturing
The so-called “facility of the future,” concludes Nestola, would allow rapid changeovers due to its modular approach and because it is fit by design to accommodate single use and minimize any possible…

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