Search results for " virus" in Articles / App Notes
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Platform Technologies Improve Protein Expression
Platform technologies facilitate development and accelerate commercialization of protein therapeutics.
By Cynthia A. Challener
Speed to market is essential in the biopharmaceutica…
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Improvements in Protein A Chromatography
… provides high yield while providing up to 3 logs of host cell protein removal and 4 logs of DNA and virus removal. Resins are robust enough to be cleaned with caustic and re-used hundreds of times. …
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Witnessing Major Growth in Next-Generation Antibodies
The company also has a drug in development (ALX-0171) for the treatment of respiratory syncytial virus (RSV) infection in infants. This product is attractive because it is sufficiently stable for admi…
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Generating a Fully Processed Antibody
These include molecules such as virus-like particle (VLP) vaccines, proteins that require cleavage, or other additional post-translational modifications not typically performed by Chinese hamster ovar…
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Selection Guide Size Exclusion Chromatography Columns and Media
A variety of media with different selectivities are available and cover a molecular weight range from Mr 100 to 100 000 000, from peptides to very large proteins, protein complexes, and virus.
D…
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Lessons Learned Accelerate Vaccine Development
Early bioprocessing challenges
The diversity of viruses that cause diseases, the number of different vaccine products, and the variety of vaccine production methods all contribute to the complexit…
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Capto™ Core 700 in Vaccine Processing
The aim with this white paper is to discuss the advantages of using Capto Core 700 in virus purification compared to size exclusion chromatography (SEC), a technique commonly used in several vaccine…
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Risk Assessment and Mitigation in Biopharmaceutical Manufacturing
For example, when assessing initial and post-mitigation risks as part of the manufacturing plant’s control strategy for virus contamination prevention, there is likely no previous occurrence within a …
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A Bright Future for the Plasma Fractionation Industry
Three opening presentations dealt with the Hepatitis E Virus (HEV) issue from a risk, regulatory, and safety point of view. The take-home message was that the efficacy of plasma manufacturing steps fo…
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Modular Manufacturing Platforms for Biologics
Caliber has received inquiries from government officials about whether it could help manufacture ZMapp, a treatment to fight the Ebola virus. Caliber uses G-CON’s pods for its entire downstream proces…