Search results for " productivity"
Article
Exosome isolation by tangential flow filtration and size exclusion chromatography
- High productivity, scalability, and single-use compatibility were observed for the superSEC resin.
- Scaling up the SEC resin volumes using the superSEC resin was clearly shown with shorter pur…
Article
Video: The solution to smarter column packing
Packing modern chromatography resins at large scale requires a column capable of axial compression to ensure stable, reproducible packed beds. AxiChrom™ columns are low-pressure, axial compressi…
Article
Discovering the unknown: How does in silico process development change PD scientists’ work?
This resulted in improvements in purity and yield of a mixed mode chromatography purification step, and doubled productivity. Mechanistic modeling can also support early-phase development. The technol…
Article
A scalable single-use two-step plasmid purification process
The current global demand for biopharmaceuticals is over USD 300 billion, with an estimated growth of ≥ 12% annually. While MAb processes have become much more efficient, production of mRN…
Article
Report from the 6th International HTPD Conference
The biggest challenge is still the people and Quantitative Structure-Activity Relationship (QSAR) plus mechanistic modeling were two key take-home messages from the 6th International conference devote…
Article
Process Development for Viral Vectors
Download a case study from Fast Trak™ process development services team to learn more about how a platform process and experienced team can accelerate development timelines and increase productivity.
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Article
A Look into Biologic Scale-Up Strategies
Optimizing cell-culture processes for monoclonal antibody (mAb) production is a key factor in scaling up manufacturing to commercial levels. To maximize cell-culture output, strategy is requir…
Article
High-concentration monoclonal antibody drugs: manufacturing challenges
The growth in the formulation of drugs suitable for delivery by subcutaneous (Sub-C) injection highlights manufacturing challenges associated with the higher concentration of active ingredient…
Webcast
Xcellerex™ X-platform bioreactor live virtual demo
Whether in pilot or cGMP facilities, the modular and application-based approach improves cell culture productivity.
In this virtual workshop Ken Clapp will explain how we developed the Xcellerex™ X…
Article
Weighing the Benefits of Single-Use Consumables
While the debate between stainless steel and single-use systems (SUS) will continue to rage for the foreseeable future, most would agree that there is a time and place for either approach. Nat…