Search results for "development"
Article
Tapas & TECH Talks: Panel Discussion with Cytiva/IQVIA
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When developing a new therapy, it is more important than ever to have the future in mind from the outset. The choices you make at each step can set you up for …
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Protein A Fiber Chromatography from Research to Scale-up and Manufacturing of Monoclonal Antibodies
This makes the pre-packed, small-scale Protein A fiber unit a versatile tool for processes such as clone selection and upstream cell-culture media development. The time savings in downstream processes…
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Improving Lentiviral Vector Downstream Processing Workflows
This article discusses process development pain points of a modern workflow and ways to address them.
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Rapid Cycling Protein A-Based Fiber Chromatography to Address Emerging Downstream Bottlenecks
Fibro PrismA is a new protein A fiber chromatography format developed to complement traditional resin-based chromatography. The protein A fiber matrix has an open pore structure in which mass transf…
Article
New Therapies Present Scaling Challenges
New Therapies Present Scaling Challenges
Manufacturing differences between traditional mAb therapies and newer biotherapeutics dictate whether processes should be scaled up, scaled out, or use an al…
Resource
Plasma Product Biotechnology Conference
The sessions, compiled from submitted presentations, will cover the areas of manufacturing, quality, regulatory, pathogen safety, clinical development and technical innovations, and will chaired by re…
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Preclinical Evaluation of Product Related Impurities and Variants
Preclinical Evaluation of Product Related Impurities and Variants
The approaches for sample preparation of preclinical evaluation of safety and efficacy are addressed taking into consideration the s…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
Where the productivity of the cell line is equivalent in fed batch and perfusion, then the balance favors fed batch based on efficient media utilization and easier development. Perfusion has potential…
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Real Time Continuous Microbiological Monitoring
The results are obtained after enough days of incubation allow the development of colonies to be counted by visual inspection. The results are then expressed as colony forming units (CFU) per unit of …
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Perfusion in the 21st Century
Contamination issues have also been significantly reduced with the development of aseptic connections.
Cell separation devices have also become more efficient, allowing for very high cell densitie…