Search results for " bioreactor" in Articles / App Notes
Article
Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
This application note describes the validation of the single-use ReadyToProcess WAVE 25 rocking bioreactor system in production of influenza virus from Vero cells in microcarrier-based cultures. A 2…
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ReadyToProcess WAVE 25 Bioreactor System
The system is based on a well-known rocking technology that provides mixing and aeration to the culture, which is maintained in an inflated, disposable Cellbag bioreactor cultivation chamber.
With…
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Scaling a mAb production process to Xcellerex bioreactors
Moving a monoclonal antibody production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Scaling a mAb Production Process to Xcellerex Bioreactors
This article discusses moving a monoclonal antibody (mAb) production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
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Article
Lentiviral Vector Upstream Process in Single-use Bioreactors
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Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction efficiencies, ability to infect both dividing and nondivi…
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Process Development and Optimization Using the ReadyToProcess WAVE™ 25 Bioreactor System in Dual Mode
Download this application note to learn about the technical feasibility of the Method editor and operations in dual mode (where two parallel cultures are controlled independently) are demonstrated. …
Article
Single-Use Technologies Prove Effective for Viral Vector Process Development
Overall process scalability and robustness, says Todd Sanderson, senior R&D manager for Pall Biotech, are dependent on the performance of the bioreactor whether it is adherent- or suspension-based. “T…
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Tools for Continuous Bioprocessing Development
If the large-scale bioreactor is well characterized, a small-scale system can be used to replicate all of its operating conditions and potential variations. Proper scale down requires good simulation …
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A Plastic Pipeline for Commercial Bioprocessing?
“Single-use bioreactors, currently available in sizes up to 2000–4000 L, are a potential solution when looking for smaller vessel capacities,” says Joe Prado, director, cGMP biomanufacturing operation…
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Improving Upstream Predictability
Today, better understanding of cells and how they interact with their environment has enabled improvements in most aspects of upstream processing, from bioreactor design and media development to proce…