Search results for "Mabs" in Articles / App Notes
Article
Optimization of an antibody polishing step
Antibody purification processes are typically developed using a platform approach. Optimal operating conditions for single units are found by altering just a few process parameters with De…
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Bispecific Antibodies are Moving from Research to Clinical Development
With recent approvals of bispecific antibodies, these complex molecules are fast moving out of the research box and into clinical pipelines.
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Navigating Molecular Diversity
Are you working with biomolecules beyond mAbs?
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Getting Started with Fibro PrismA - Free e-Learning
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Are you using resin-based columns? Fibro PrismA units for rapid cycling chromatography connect to ÄKTA™ systems in the same way. Additionally, you can use the s…
Article
Commercial Production of Gene Therapies Using Suspension or Adherent Cell Lines
The rise of therapeutic monoclonal antibodies (mAbs) in the 1980s drove the requirement to adapt Chinese hamster ovary (CHO) cells to suspension in order to allow the use of stirred tank bioreactor fo…
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Process Development: Go Smarter, Go Faster! Available on Demand
Did you miss our virtual symposium? We heard from leaders at GlaxoSmithKline, Byondis, UCB, UCL, GoSilico, and Cytiva on how they balance innovation, speed, and robustness to accelerate their p…
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Guide to Polishing Chromatography in Process Development
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This article shares the factors you should consider when developing your polishing steps—from the basics to the typical challenges faced, and how to overcome them.
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Meeting the Process Development Challenges of a Diverse Biologic Pipeline
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In the current biopharmaceutical landscape, developers are constantly encountering new and diverse biological molecules with complex structures. While these novel biolog…
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Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Peggy Lio, Cytiva
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Peggy Lio, Senior Director of Global Cell Culture Services at Cytiva, explores the evolution of b…
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What If You Could Remove Your Antibody Aggregates Already in the Protein A Step?
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In this study, the potential of Protein A chromatography to separate antibody monomer from HMW species was investigated. A design of experiments approach…