Search results for " bioprocessing" in Articles / App Notes
Article
Under pressure: exploring root causes of leaks in single-use mixers
Here we’ll take a look at some of the most common causes for leaks in single-use bioprocessing mixers, and at some ways to prevent them.
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Article
A Closer Look at Affinity Ligands
The most common example in the realm of bioprocessing is Protein A, which has an extremely high affinity for some immunoglobulin molecules. Other examples include antibody/antigen, enzyme/substrate, a…
Article
What is process development?
What is process development?
Biopharma process development comprises the activities that help you create a series of steps to produce a biomolecule – a monoclonal antibody (mAb), recomb…
Article
Enhancing Resins Addresses Purification Concerns
Christoph Burgstedt/Stock.Adobe.com
Enhancement of resin technology can improve the ability of chromatography to purify the growing landscape of increasingly complex biomolecu…
Article
Cell-free Expression Systems Pose Cell Culture Alternative
Feliza Mirasol
Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product of cell culture. One approach that potentially offers the benefit of a “cleaner”…
Article
Common Challenges in Cross-Functional Process Development
Topic covered include:
1:28 – Common stumbling blocks in developing an effective bioprocessing operation
2:18 – Should upstream and downstream processes be developed concurrently or sepa…
Article
Basics in Process Development for Biotherapeutics
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Definitions, activities, and things to consider when developing an upstream or downstream bioprocess.
Article
Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Peggy Lio, Cytiva
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Peggy Lio, Senior Director of Global Cell Culture Services at Cytiva, explores the evolution of b…
Article
The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges.
By Kelvin H. Lee and Mark Lies
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Article
Developing a Closed, Connected Single-Use mAb Purification Process
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Learn more on this case study to set up a closed and connected single-use monoclonal antibody (mAb) purification process that addresses a perfusion upstream process. In the Pr…