Search results for " disposable" in Articles / App Notes

Article Being Thorough When Transferring Technology
Communication and taking the time to develop the process are key to successful transfer and scale up of biologics. By Susan Haigney Editor's note: The following is an extended version of the…

Article Speed and Flexibility Are Dual Goals for Biopharma Operations
Bioprocessing facilities, equipment, and materials, as well as strategies to improve biopharmaceutical development and manufacturing, were featured at INTERPHEX 2017, held in March in New York City.…

Article Cost Considerations Drive Lean Technology in Biopharmaceutical Manufacturing
By Catherine Shaffer Four biosimilars have been approved for the market by FDA as of February 2017, and more are in the pipeline. Now that biosimilars are here to stay, manufacturers are devel…

Article Ensuring the Biological Integrity of Raw Materials
Single-use manufacturing devices, disposable consumables, and ready-to-use reagents and media are also reducing rates of contamination in the industry. Faster, more accurate tests are being introd…

Article Improving Process-Scale Chromatography
“Initially, many people in the industry expected disposables to be less environmentally sound than traditional technologies, but our studies have revealed the opposite,” she observes. Most notably, si…

Article Design and Qualification of Single-Use Systems
…integrity properties, sterilizability, drainability, incorporation into an automated platform as the disposable fluid path, etc. • Manufacturability ensures that the SUT production equipment and …

Article Managing Biomanufacturing Capacity Expectations
Capacity for complex therapeutics is becoming increasingly difficult to predict. By Randi Hernandez Demand for any given new product is typically only known after significant investments h…

Article Lessons Learned Accelerate Vaccine Development
In addition, disposable technologies offer the potential to eliminate equipment cleaning, process cleaning validation, and cross-contamination, plus facilitate changeovers between processes, according…

Article Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies
The system consists of two bench-top chromatography instruments connected to a central unit with eight disposable filtration devices used for loading and filtering the cell cultures. The staggered par…

Article Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
Further, an evaluation of the effect of the integrated, disposable mixer bag impeller on chromatography media particles was performed. The results show that XDM Quad Mixing System is suitable for use …

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