Search results for " Biopharm" in Articles / App Notes
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Paring Down Impurities in Downstream Processing
Myriad choices confront manufacturers before they even consider optimizing downstream processes. Each decision directly influences what final options will be available on arriving at the final…
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Right the First Time: Bioreactor Scale and Design Translation
Cell culture process transfer requires a good understanding of the physicochemical conditions within a bioreactor. This includes the hydrodynamic environment induced by the agitator and the …
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Selecting Chromatography Resins for Bispecific Antibody Purification
Targeting enhancement with two active antibody arms makes bispecific antibodies (bsAbs) highly attractive for the treatment of cancer and other diseases. Their purification can be more challen…
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Democratizing GMP Manufacturing for the New Therapeutic Pipeline
PharmTech Europe discusses technology that enables the “democratization” of mRNA manufacturing with Scott Ripley, general manager, Nucleic Acid Therapeutics and Precision Nanosystems, Cytiva, …
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Discussing the Origins of the mRNA Therapeutics Field
Andy Geall, co-founder and chief development officer at Replicate Bioscience, discusses the historical context and buildup of the mRNA therapeutics field.
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ML and AI Implementation Insights for Bio/Pharma Manufacturing
A recent survey of biopharma industry manufacturing leaders found that creating machine learning (ML) and artificial intelligence (AI) solutions catering to manufacturing segments can quickly…
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A Look into Biologic Scale-Up Strategies
Optimizing cell-culture processes for monoclonal antibody (mAb) production is a key factor in scaling up manufacturing to commercial levels. To maximize cell-culture output, strategy is requir…
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Innovations in Downstream Processing
Innovations in downstream processing accelerate development, enhance efficiency, and promote sustainability.
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Balancing AAVs Versus LLVs
Knowledge of adeno-associated variant's infection pathway is based on only a few serotypes. The prevailing understanding is that serotypes bind to different, or have differential affiniti…
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mRNA Global Alliance Tests the Waters at BIO
World leaders have set ambitious goals to respond more swiftly to the next pandemic, including the US goal to design, test, and review a new vaccine just 100 days after a pandemic declaration.…