Search results for " Biopharm" in Articles / App Notes
Article
The Tide Stays High
Nevertheless, fundraising by emerging biopharma companies held its own in 2016. Financing for emerging bio/pharma from venture capital, public equity, and partnering sources was ahead of 2013 levels, …
Article
Improving Process-Scale Chromatography
By Cynthia Challener, PhD
Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a significant portion of downstream processing efforts (time and cost) for bio…
Article
Establishing Acceptance Criteria for Analytical Methods
Knowing how method performance impacts out-of-specification rates may improve quality risk management and product knowledge.
By Thomas A. Little, PhD
To control the consistency and quality o…
Article
Real Time Continuous Microbiological Monitoring
Laser-induced fluorescence, a rapid microbiology method for real-time airborne particle and microbial monitoring, enhances sterility assurance in pharmaceutical manufacturing.
By Claudio Denoya …
Article
Modeling Bioreactor Performance
Why model bioreactor performance?
There are many reasons why biopharmaceutical manufacturers invest in the development of bioreactor modeling capabilities. Modeling is used to gain insight into no…
Article
Innovation vs. Capacity: How CMOs Compete
Perhaps the biggest is the reduced propensity of global bio/pharma companies to outsource manufacture of their newest products, especially biopharmaceuticals. New product approvals earned by global bi…
Article
Perfusion in the 21st Century
By Bruce Lehr, Delia Lyons
Cell-culture technology for biopharmaceutical manufacturing has steadily advanced over the past three decades. Batch processing, in which all raw materials are introduce…
Article
Downstream Processing Continues to Worry CMOs
…ppear to show any signs of abating, according to BioPlan Associates 13th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production
(1). In fact, nearly two-thirds (64%) …
Article
Generating a Fully Processed Antibody
By Gregory Bleck, Dona York, David Rabuka
The number of more complex biopharmaceuticals in development continues to increase. These include molecules such as virus-like particle (VLP) vaccines, pr…
Article
Analysis of Glycosylation in Biosimilars
A step-wise process is used to characterize glycans and understand the functioning of a molecule for biosimilar development.
The structures of protein drugs such as monoclonal antibodies are mad…