Search results for " growth"
Article
CMOs Concerned With Cost of Single-Use Equipment
Is single-use too expensive?
The relatively rapid growth in use of single-use equipment for early-stage (and increasingly commercial stage) manufacturing may suggest that costs are considered reas…
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Best Practices in Qualification of Single-Use Systems
For example, a single-use bioreactor should be sterile and not adversely affect cell growth due to certain leachables. It should provide sufficient mixing and have acceptable gas exchange, and should …
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Selecting a Comprehensive Bioburden Reduction Plan
Understanding the basics of microbial growth and routes of contamination is key to effective management independent of the products manufactured. Bioburden problems often result from a lack of underst…
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Cleaning of Dedicated Equipment: Why Validation is Needed
Finished surfaces should be smooth and properly polished, and equipment should be appropriately designed and assembled in a way that facilitates cleaning and prevents microbial growth (i.e., no dead l…
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Advanced Technologies Facilitate Scale-up and Technology Transfer
In addition, the culture growth takes place over a long period of time. As a result, a reactor for mammalian cell culture is not required to have high heat removal or provision for high oxygen supply;…
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Ensuring the Quality of Biologicals
monographs that cover the product classes of human growth hormone, granulocyte colony-stimulating factor, erythropoietin, and insulin. Although the Ph. Eur. recognizes that monographs provide public s…
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Drug Discovery and Development in India
The growth of the local pharmaceutical research and development sector can serve as a key driver of economic growth, and this will help increase income levels and improve the access to healthcare serv…
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Trends in Single-use Bioreactors
One molecule identified by Amgen employee Matthew Hammond found bDtBPP to be detrimental to the growth of a number of strains of Chinese hamster ovary cell lines.
Galliher (Cytiva): Some barriers …
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Optimizing Resin Performance with Disposable Chromatography Solutions
Market Trends
BioPharm: How is the market reacting to disposable chromatography solutions? Do you see growth? In what areas?
Royce and Lundström (Cytiva): The highly regulated biopharmaceutica…
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Healthcare Reform in China
In fact, it is poised to become the second largest market in 2015 given that its annual growth rate of sales is between 15 and 20%, according to Yanzhong Huang, a senior fellow of global health at the…