Search results for " chromatography"
Article
Making the Move to Continuous Chromatography
Some regulatory aspects must still be addressed, however, and for companies with extensive existing infrastructure, switching to continuous chromatography might not be cost-effective.
Continuous v…
Article
Improving Process-Scale Chromatography
Advances are being made on several fronts to reduce the time and cost associated with large-scale chromatography. The development of new resin chemistries including enhancements to Protein A for monoc…
Article
Process Chromatography Selection for Downstream Processing Applications
By Caroline Hroncich
Process chromatography has changed significantly since it was first introduced to the biopharmaceutical industry. Important factors such as column design, resin development, a…
Article
A Look at the Affinity Chromatography Landscape
With the advent of next-generation biopharmaceuticals, chromatography material suppliers have been challenged to develop affinity ligands and support systems that enable the separation and purificatio…
Article
Process Chromatography: Continuous Optimization
A combination of chromatography steps using different resin chemistries is used to purify the biologic drug substance to an acceptable level. The number and types of chromatography steps depend on the…
Article
Evaluating the Use of Continuous Chromatography
In downstream processing, continuous chromatography is gaining traction in the purification of protein therapeutics. As the biopharmaceutical industry strives to demonstrate, continuous manufacturing …
Article
Reducing Cross-Contamination Risks in Process Chromatography
Single-use solutions for process chromatography are no exception and offer distinct advantages over permanent, stainless-steel systems in many circumstances.
Reducing risk
Manufacturer…
Article
Technology Innovations Improve Process Chromatography Performance
Biomanufacturers consider several key factors when selecting a best-fit process chromatography technology for their products, including the stability of the biologic, compatibility of the buffers used…
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
…y, vice-president of sales and marketing, bioprocessing, Repligen about current trends in disposable chromatography and how the technology will change bioprocessing in the future. The experts address…
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HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
This article discusses recent advances in high-throughput and multi-product liquid chromatography and electrophoretic methods for protein characterization. In addition to advances in analytical method…