Search results for " equipment" in Articles / App Notes
Article
Scaling Up Novel Therapies
Chromatography and filter manufacturers have developed scalable and reproducible low-volume mimics of their industrial-scale equipment, which allow more accurate scale-up work than ever before, he say…
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A Plastic Pipeline for Commercial Bioprocessing?
Lower capital costs for facilities and equipment, lower operating costs, smaller equipment footprints, lower overhead costs, flexibility of system configurations, faster changeover times, the reductio…
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State of the Biopharmaceutical Industry: Lessons from 2018 Survey Data
For example, our studies have shown rather consistent incremental increases in upstream cell culture titers over the past three decades; and it took well over a decade for single-use equipment to atta…
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Hybrid Bioprocessing: A Q&A with Andrew Sinclair
… have lower costs, smaller footprints less support infrastructure, but they still have some reusable equipment. The key benefits are derived from decoupling process equipment from building (i.e. havi…
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Automating Bioprocesses
By Jennifer Markarian
Both upstream and downstream biopharmaceutical processes have conventionally used stainless-steel equipment, but use of single-use systems (SUS) is becoming more established.…
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Safety Drives Innovation in Animal-Component-Free Cell-Culture Media Technology
…ures to toxic contaminants, metabolic waste products, or leachables from polymers used in single-use equipment and flexible packaging films (24, 25). It has been difficult to identify functionally eq…
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Automation Trend in Fill/Finish Reduces Contamination Risk
Because aseptic filling requires close coordination and involves complex interaction between personnel, sterilized product, the fill/finish equipment system, the cleanroom—including support facilities…
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Understanding Validation and Technical Transfer, Part I
“In its simplest form, a process is a blending or a transformation of inputs such as people, materials, equipment, methods, and environment into outcomes. Some of these inputs do the transforming and…
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Perfusion in the 21st Century
These drugs are often produced in smaller, more flexible facilities that are designed to manufacture multiple products, and often involve the use of disposable equipment. Biosimilars manufacturers are…
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A Q&A on Bioprocessing Trends and Technologies at INTERPHEX 2016
A number of equipment manufacturers announced new bioreactors, fermenters, tanks, and other process-related equipment as the move toward single-use systems in commercial manufacturing moves forward.
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