Search results for " market"
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Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
Although Protein A resins introduced to the market in the last 10 years withstand low to medium concentrations of sodium hydroxide for cleaning, like 0.1 M sodium hydroxide and in some cases 0.5 M, th…
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Process Chromatography: Continuous Optimization
Metal chelate, size-exclusion, and hydroxyapatite resins are also used on a limited basis, according to Andrew Bulpin, head of process solutions strategic marketing and innovation with MilliporeSigma.…
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Contract Manufacturing Through the Years
Emerging bio/pharma companies rode the coattails of Internet companies to gain access to venture capital and the market for initial public offerings (IPOs). Those early stage companies were unable or …
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Unifying Continuous Biomanufacturing Operations
Some of these benefits could fluctuate based on market trends, however. As Klutz et al. pointed out, if resin prices were to come down, downstream continuous manufacturing might no longer offer an eco…
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Fusion Proteins Pose Manufacturability Challenges
A variety of different fusion proteins have been evaluated in clinical trials and several products are on the market. Amgen’s Enbrel (etanercept) for the treatment of moderate to severe plaque psorias…
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Speed and Flexibility Are Dual Goals for Biopharma Operations
With speed to market a prime objective, prefabricated and modular production facilities, with shorter construction times, are being viewed as alternatives to conventional construction. Specialized the…
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Accelerated flavivirus vaccine production with modern tools and solutions
Single-use production bioreactors and chromatography purification columnsmitigate cross-contamination risk and support increased operator safety, while reducing time to market by eliminating costly an…
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Ensuring the Biological Integrity of Raw Materials
Faster, more accurate tests are being introduced to the market to address the problem of contamination. “Traditional test methods require up to seven days for reliable results,” Theresa S. Creasey, Mi…
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Advancing Single-Use Technology Through Collaboration
Single-use systems minimize the risks for cross-contamination between batches, can be set up more quickly than traditional fixed systems, can lower operating costs per batch, and may allow for market …
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Establishing Acceptance Criteria for Analytical Methods
In practice, no company will release to the clinic or to the market the mean or theoretical concentration; one releases every batch, tablet, vial, and syringe.
What therefore should be the basis f…