Search results for " formulation" in Articles / App Notes

Article What’s in your media? How costly is variability of cell culture media to your manufacturing process?
For example, we have a formulation, and they are concerned about nickel— we look at these nickel content in these batches. For example, the nickel is coming in primarily through an amino acid componen…

Article Need solutions for large-scale production of mRNA-based molecules?
Therapies based on messenger RNA, such as mRNA vaccines, have revolutionary potential. mRNA therapeutics offer precise and individualized therapy and avoid manufacturing issues associated wit…

Article Cell-free Expression Systems Pose Cell Culture Alternative
That complexity ranges from the creation of a master cell bank all the way to manufacturing at scale, product recovery and purification, and, finally, product formulation, according to a group comment…

Article The Importance of Process Intensification and PAT for Achieving Real-Time Release
Creativity and collaboration are required to overcome complex method development challenges. By Kelvin H. Lee and Mark Lies …

Article Cytiva and 4Tune Engineering Collaborate on Cell Therapy Quality Risk Management
The collaboration addresses the need for risk mitigation plans in cell therapies. On Dec. 3, 2020, Cytiva and 4Tune Engineering, a manufacturing-sciences and technology company, announced that th…

Article How To Execute Successful Data Migrations
…, how far back will a company need to maintain manufacturing logbooks and specifications for retired formulations?  On many levels and for many reasons, the amount of data and documents tha…

Article Technology Innovations Improve Process Chromatography Performance
Additionally, current Protein A product formulations require flammable chemicals for storage and transportation, which require specific safety precautions and incur additional shipping and handling co…

Article Considerations for Optimizing Process Development
Click here to read the article >> Intensify your cell culture processes to keep pace with today’s industry and regulatory expectations.

Article Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
When combined with innovative new technologies such as in-line dilution, single-use powder and liquid formulations can help reduce facility footprint, labor hours, and the overall cost of goods.  …

Article Eliminating Residual Impurities Starts with a Strategic Plan
…norganic or organic contaminants from permanent and single-use process equipment, the pharmaceutical formulation, and/or a breach of sterility. “A strategy for the control of residual impurities has …

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