Search results for " protein" in Articles / App Notes
Article
The Importance of Partnering for Bioanalytical Studies
…munogenicity assay may not have a confirmatory tier as an immune response is expected from a foreign protein. Perhaps you have a novel cell therapy, and a flow cytometer is used to collect ‘cellular …
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Speeding Up mAb Purification Using Fiber-based Technology
Learn how to automate high throughput monoclonal antibody (mAb) purification and improve throughput significantly using fiber-based chromatography.
With purification cycles in minutes rather th…
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Cytiva Expands Offering for ReadyToProcess™ Columns
ReadyToProcess columns are offered in seven inner diameters to meet the needs of upstream production. You can enjoy the flexibility of using our prepacked ReadyToProcess columns from benchtop to ful…
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Cytiva and GoSilico Agree to Co-market ChromX™ Mechanistic Modeling Software
The agreement facilitates the adoption of ChromX™ by scientists and users of resins, columns, and chromatography systems into their downstream process-development workflows to accelerate development…
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Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
By establishing effective management of data and knowledge, it will be possible to employ advances, such as artificial intelligence and synthetic biology, to their full potential in upstream bioproc…
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Epitope Binning: A Critical Step in Antibody Selection
Read about how surface plasmon resonance (SPR) is used to characterize closely related “bins” of monoclonal antibodies (mAbs) targeting the same epitope of the target protein, and how the selection …
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The Evolving Role of Starting Materials in Cell and Gene Therapy
Unlike other biological drug products such as therapeutic proteins, monoclonal antibodies, or vaccines, drugs based on living cells are by nature uniquely vulnerable to supply chain complications and …
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A Continuous Confidence Boost
Continuous processing of monoclonal antibodies (mAb) could offer a number of advantages, but regulatory uncertainty and upfront investment remain sticking points.
In this case study, Shanghai Henli…
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Risk Assessment: Studying Chromatography Resin Variability
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Many factors can give rise to process variability, such as variation in different process parameters or raw materials. This article focuses on process robu…
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New Therapies Present Scaling Challenges
In the case of gene therapy, the resins would be specific to the capsid protein. The downstream purification aspect lends itself nicely to standard purification technology. Although there are many tec…