Search results for " Mab"
Article
Technical and Process Economical Aspects of Using Capto™ Q and ReadyToProcess™Adsorber Q in mAb Polishing
… packed in conventional chromatography columns when used in the final polishing step of a three-step mAb purification process. To identify scenarios for beneficial use of each of these product altern…
Poster
Optimizing dynamic binding capacity and aggregate clearance in an mAb polishing step
Capto™ S ImpAct is a strong cation exchange (CIEX) chromatography medium (resin) designed for monoclonal antibody (MAb) polishing steps. In this study, optimization of binding conditions targeting h…
Article
Life cycle assessment of the protein A process in mAb manufacturing
Here we present a cradle-to-grave LCA for protein A chromatography resins in the capture step of mAb manufacturing. The focus is on the resin use phase, although resin manufacturing, packaging, distri…
Article
Exploring the world of antibodies: mAbs, Fabs, dAbs, and bsAbs
Developing purification processes for antibody variants is not always straightforward and the platform approaches conveniently used for many traditional mAbs cannot be used.
Learn more about develo…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAb at Large Scale
Read more>>
As process intensification is adopted into large-scale manufacturing, the responsibility on scale-down models to accurately represent the expanded operating space quickly follow…
Resource
Accelerate mAb Process Development with Fibro Rapid Cycling Chromatography
Results in minutes, not hours: That’s one of the ways protein A fiber chromatography opens new opportunities in downstream process development for mAbs. In this webcast, Cytiva experts discuss how y…
Article
WEBCAST ON DEMAND: Accelerate mAb Process Development with Fibro Rapid Cycling Chromatography
Watch webcast >>
Results in minutes, not hours: That’s one of the ways protein A fiber chromatography opens new opportunities in downstream process development for mAbs. In this webcast, Cytiva e…
Article
A Small-Scale Model to Increase Yield in Cell Culture Perfusion of mAbs at Large Scale
Click here to learn more >>
We have developed a reliable small-scale model for a monoclonal antibody (mAb) perfusion process using TPP® TubeSpin® Bioreactor tubes and the ReadyToProcess WAVE 25 R…
Article
Scaling a mAb Production Process to Xcellerex Bioreactors
This article discusses moving a monoclonal antibody (mAb) production process from a microscale bioreactor to the Xcellerex XDR single-use platform.
Learn more >>
Article
Case Study: High Throughput mAb Purification Using Fibro
In this case study, a drug discovery lab at AstraZeneca finds that purifying antibodies with Fibro PrismA means they can screen more candidates per week with a simpler equipment setup.
Click here…