Search results for "automated" in Articles / App Notes
Article
The Challenge of Disruptive Technologies in Bioprocessing
“Automation has the opportunity to close the gaps of determining how to scale up a process that was created with simple lab equipment to one that is run in a sophisticated and automated manufacturing …
Article
Monitoring and Control of Inline Dilution Processes
“The advent of buffer concentrates delivered in single-use (SU) bags combined with automated, compact precision dilution and blending technology allows these tank farms to be repurposed for more produ…
Article
Moving PAT from Concept to Reality
PAT can account for the variations and peculiarities of the cells from different patients in an automated fashion, enabling a high process consistency irrespective of the starting material.
PAT ca…
Article
Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
…analytics such as titer measurements and improve the ability of real-time analytics to enable fully automated process control (4). Other innovations include single-use sensors such as the Rosemount 5…
Article
HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
Recently, automated 2D Protein A–SEC methods for the purification and analysis of MAbs have been developed.28,29 In these methods, multiple protein separation steps were performed automatically. Sampl…
Article
Improving Upstream Predictability
Univercells has leveraged process intensification in a new single-use bioreactor design that features a structured fixed-bed bioreactor connected to an automated tangential flow filtration concentrato…
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Mapping a Route for Cell and Gene Therapy Process Development
Reducing manufacturing costs, as well as development of scalable, automated manufacturing processes under closed systems that can reach the target quantities while maintaining the critical quality att…
Article
Taking a “Development-by-Design” Approach to Cell Therapies
Figure 1: Part of an automated solution being developed by NeoStem and Invetech. Automating processes is key to reducing costs (courtesy of Invetech).
“We are not trying to be two different comp…
Article
Maximum Output Starts with Optimized Upstream Processing
On a positive note, parallelization of experiments using automated systems for high-producer clone selection, along with medium optimization and the availability of standard kits, are having an overwh…
Article
Improving PAT for Biologics
Sartorius recently extended its bioreactor portfolio with automated glucose-feed-control and integrated real-time measurement of viable cell density for automated induction, infection, and harvesting …