Search results for "Cytiva"
Article
New to mRNA manufacturing? Here's what you need to know
Click above for an in-depth guide on mRNA manufacturing.
Article
Rethinking ion exchange chromatography modeling
In the early days of modeling, mechanistic models for ion exchange chromatography were mostly based on stoichiometric equations. A new adsorption isotherm class was introduced in 2021: the co…
Article
Webcast: How to study membrane protein interactions
Learn how Anna Moberg studies activity and function of extracted membrane proteins.
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Article
Accelerating VLP purification process development
See how using mechanistic modeling can speed up the purification process development of virus-like particles (VLPs).
Indeed, a method for the large-scale production of VLPs is produ…
Article
e-Learning: what is quality by design (QbD)?
This free interactive course shares what quality by design (QbD) is all about. The focus lies on applying QbD to process development of biopharmaceuticals.
Key learnings:
- Fundamen…
Article
Virus and exosome purification: harness core bead technology
Using core bead technology to fine tune impurity removal and maximize recovery of
large entities.
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Article
Engage a mechanistic modeling expert – or become one
The application of mechanistic modeling requires expertise for effective use. When planning to implement this ground-breaking technology one essential question must be addressed befor…
Multimedia
Q&A: Oligonucleotide synthesis in process development and scale-up
In this video, Greg Farlow, RNA/DNA synthesis product specialist at Cytiva, talks about the typical challenges with oligonucleotide synthesis in process development and key considerations when scaling…
Article
Adsorption isotherm models for chromatography
Read on commonly used models for the thermodynamics of adsorption within a chromatography column.
Indeed, in order to create a complete chromatography model, the adsorption of compon…
Article
Optimizing capture and polishing steps in an rAAV purification process
In this article, we show how we developed an efficient purification process for recombinant AAV (rAAV). The chromatography purification described includes affinity capture to maxi…