Search results for "Cytiva"
Article
Key Process Considerations for Therapeutic Oligonucleotides
Click here to read the article >>
Learn more about scalable solutions for developing and manufacturing oligonucleotide therapeutics.
Webcast
Strategies and emerging technologies for mAb capture
In this webinar we will describe and evaluate different process intensification strategies for the mAb capture step. Strategies will depend on the mode of upstream operations (fed batch or perfusion…
Webcast
A route to deeper process understanding-Studying resin variability using a Process Characterization
Process robustness and success requires a thorough understanding of critical process parameters (CPP), critical material attributes (CMA), and sometimes interactions between these. Chromatography resi…
Article
Achieving the Required Buffer Quality with Inline Conditioning
Buffer production often becomes a limiting factor when the goal is to design more flexible facilities. To overcome this, Janssen Biologics BV decided to investigate inline conditioning (IC) technology…
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
Access study data here…
Article
How Do I Fix Asymmetrical Chromatography Peaks?
All good chromatography books say that the peaks in the chromatogram should be symmetrical, but what about real life in the lab? There are many different causes to “fronting” or “tailing” peaks, but…
Article
How to Optimize and Scale Up AAV Production
In this article from a roundtable discussion, four experts from academia and industry met to discuss challenges in refining and scaling up AAV production pipelines to meet the increasing demand for …
Article
Troubleshooting Protein Purity Issues – Top Tips
Click here to learn more >>
What’s the point of protein purification? Obtaining pure proteins, of course! If you are having difficulties obtaining the purity you need, these troubleshooting tip…
Article
The Role of CDMOs in Cell and Gene Therapy Process Development
Click here to read more >>
An experienced contract development and manufacturing organization (CDMO) can ease scaling and tech transfer.
Article
Efficient Sodium Hydroxide Sanitization with a Novel Procedure of AxiChrom™ Columns Packed with Chromatography Resin
Read full study>>
Sodium hydroxide (NaOH) cleaning-in-place is the widely accepted method of sanitization employed by biopharmaceutical manufacturers to avoid the excessive costs and delays of a…