Search results for "Cytiva"
Article
Sanitization of ÄKTA™ pilot 600 Using Sodium Hydroxide
The ÄKTA pilot 600 chromatography system is designed to facilitate sanitization, with the high standards imposed by regulatory authorities for purity of the clinical products in mind. In this stu…
Article
Combine Chromatography Techniques: Get the Right Purity/Yield of Protein
This attractive wall poster shows you how to effectively combine techniques and succeed in your protein purification.
Order now for free
Article
Full Single-Use Downstream Process? Not Any Time Soon.
Single-use technologies (SUTs) are here to stay. But where we see full single-use upstream processes, downstream is often a hybrid solution. Here’s why SUTs will not completely replace reuse systems…
Article
Freedom to Roam During Protein Purification Runs
Have you ever felt tied to your ÄKTA system and itching to get out of the lab? Consider this scenario: You have started a run in the lab and want to get some work done in your office. You may …
Article
Taking Prepacked Columns to Manufacturing Scale
Prepacked chromatography columns in biomanufacturing can save time, but also present concerns related to delivery lead times, capacity, and operational cost.
Learn more here about ways to address…
Article
How Can A Chromatography Bead Free Up Your Time?
Have you ever considered how a resin bead in your chromatography column can affect your ion exchange (IEX) chromatography run time?
Read this blog and learn how you can optimize the time spen…
Article
High Throughput Protein Purification at a Glance
Within the Human Protein Atlas project, scientists are using ÄKTA systems to purify up to 180 protein samples per week. Frida Henningson Johnson, Annelie Cajander, and Anne-Sophie Svensson sha…
Article
Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles
Presanitized and prequalified disposable chromatography columns are widely used to save time in downstream processes. However, reuse of such columns could positively impact process economy. This app…
Article
Efficient Cleaning-In-Place Methods for Protein-Based Antibody Affinity Chromatography Resins
This whitepaper discusses cleaning of affinity resins intended for use in the purification of monoclonal antibodies and antibody fragments, for example, Fab fragments. Various cleaning strategies and …
Article
Exotoxin Clearance from mAb Samples in a Two-Step Chromatography Process
A heat-stable exotoxin can remain as a contaminant of a drug substance throughout the whole manufacturing process, with the risk of adversely affecting patients’ health. One such toxin is cereulide …