Search results for "antibody"
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Selection Guide: Columns and Resins for Antibody Purification and Immunoprecipitation
Download the latest version of the selection guide Columns and Resins for Antibody Purification and Immunoprecipitation to help you select the most suitable affinity column for purifying your antibody…
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Impact of Media Components on CQAs of Monoclonal Antibodies
Balanced supplementation of amino acids has been shown to increase viable cell density and final concentration of recombinant antibody (10–12).
Carrier proteins
Carrier proteins act as a carrie…
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Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies
The growth of the segment has necessitated development of new efficient and cost saving platforms for the preparation and analysis of early candidates for faster and better antibody selection and char…
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Selecting Chromatography Resins for Bispecific Antibody Purification
Targeting enhancement with two active antibody arms makes bispecific antibodies (bsAbs) highly attractive for the treatment of cancer and other diseases. Their purification can be more challen…
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A Platform Approach to Purification of Antibody Fragments
Here, we present affinity chromatography resins that offer the possibility of a platform approach to the purification of the majority of antibody fragments. The described BioProcess™ resins offer high…
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Resolving a bottleneck in screening and characterization of recombinant antibody fragments using Biacore 4000
Biacore 4000 equipped with Biacore 4000 Antibody Extension Package has been used for efficient screening and characterization of antibody fragments for diagnostic purposes. Ten 96-well plates containi…
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Exploring the world of antibodies: mAbs, Fabs, dAbs, and bsAbs
Developing purification processes for antibody variants is not always straightforward and the platform approaches conveniently used for many traditional mAbs cannot be used.
Learn more about develo…
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Pushing the Barriers in Next-Gen Antibody Development
Continued development of new and next-generation antibodies is spurred by the increasing demand for more effective and custom-tailored biologic therapies. In particular, bispecific antibodi…
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Capture of Bispecific Antibodies and Removal of Product-Related Impurities
The biotherapeutics pipeline is becoming increasingly diverse as antibody variants such as bispecifics, conjugates, and fragments move through preclinical stages to commercial manufacturin…
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Chromatography innovations for the diverse antibody pipeline
For antibody variants, platform purification protocols for conventional mAb aren’t always providing sufficient outputs — some variants need new ligands, new base matrices, or new chromatography system…