Search results for "vaccines" in Articles / App Notes

Article Enhancing Resins Addresses Purification Concerns
Resins have been seen as one tool that can address the purification needs of new COVID-19 vaccines as well as the existing challenges in the downstream processing of increasingly complex biologic moda…

Article Microbiological Testing: Time is of the Essence
Vaccines drive test development The need for a rapid response to a possible influenza pandemic in the first decade of the 2000s spurred the development of RMMs, according to McKee. Alternative stra…

Article Unifying Continuous Biomanufacturing Operations
However, using perfusion to obtain high cell densities and increase output per bioreactor volume for the production of vaccines is of interest to researchers, too (7). No need to scale: Eliminat…

Article Ensuring the Biological Integrity of Raw Materials
Contamination of biologic drugs and vaccines by adventitious agents is extremely rare. However, when contamination incidents do occur, they can be costly in terms of time and resources. In 2010, E…

Article Pandemic Alters Policies and Practices for Drug Development and Regulation
The desperate need for new vaccines and therapies to tame the deadly COVID-19 virus required new policies and procedures for how biopharma companies select, test, and manufacture medical products—and …

Article Top Process Development Trends for 2021 and a Look into 2022
…us (AAV) production, process workflows and considerations for messenger RNA (mRNA) therapeutics and vaccines, and efficiencies in processes development. As we move into 2022, let’s take a look b…

Article High-Throughput Process Development in an Historical Environment
Conversely, Vanessa Jully from Université Catholique de Louvain in Brussels, Belgium, presented a different conclusion based on her collaboration with GlaxoSmithKline Vaccines, in which a high-through…

Article Single-Use Technologies Prove Effective for Viral Vector Process Development
“The simple reality is that the COVID-19 pandemic has shown the benefits of single-use systems in that it would not have been possible to deploy the viral vaccines in the time and the scale that has b…

Article Single-use Bioreactors Have Reached the Big Time
“Examples include traditional vaccines and blockbuster [monoclonal antibody] (mAb) biologics (>2 metric tons of mAb per year); in these cases, single-use bioreactors might not be the most efficient pr…

Article Modular Manufacturing Platforms for Biologics
G-CON Manufacturing, “G-CON Manufacturing Announces Delivery and Operation of a Custom Made POD for PaxVax, Developer of Oral Vaccines for Infectious Diseases,” Press Release, Jan. 18, 2013. 8. J.…

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